Ethanol exposure drives colon location specific cell...

Ethanol exposure drives colon location specific cell composition changes in a normal colon crypt 3D organoid model

Abstract Alcohol is a consistently identified risk factor for colon cancer. However,...

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A 3D View of Colorectal Cancer Models...

A 3D View of Colorectal Cancer Models in Predicting Therapeutic Responses and Resistance

Abstract Although there have been many advances in recent years for the...

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Alginate-gelatin-Matrigel hydrogels enable the development and multigenerational...

Alginate-gelatin-Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models

Abstract Hydrogels consisting of controlled fractions of alginate, gelatin, and Matrigel enable...

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NK cells in pancreatic cancer demonstrate impaired...

NK cells in pancreatic cancer demonstrate impaired cytotoxicity and a regulatory IL-10 phenotype

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most common tumor...

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Patient-derived organoids as individual patient models for...

Patient-derived organoids as individual patient models for chemoradiation response prediction in gastrointestinal malignancies

Abstract Chemoradiotherapy (CRT) is an important treatment modality for specific gastrointestinal (GI)...

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Organoids: An invaluable tool in pharmacology

Organoids: An invaluable tool in pharmacology

Abstract Advances in stem cell cultures and human-induced pluripotent stem cells have...

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Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis...

Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis

Abstract Pancreatic cancer (PC) is difficult to defeat due to mechanism (s)...

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Tumor derived UBR5 promotes ovarian cancer growth...

Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages

Abstract Immunosuppressive tumor microenvironment (TME) and ascites-derived spheroids in ovarian cancer (OC)...

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Patient-Derived Tumor Organoids for Drug Repositioning in...

Patient-Derived Tumor Organoids for Drug Repositioning in Cancer Care: A Promising Approach in the Era of Tailored Treatment

Abstract Malignancies heterogeneity represents a critical issue in cancer care, as it...

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