Researchers uncover two-drug combo that halts the...

Researchers uncover two-drug combo that halts the growth of cancer cells

IMAGE: Dhivya Sudhan, Ph.D., (left) and Carlos L. Arteaga, M.D. view more...

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Novel patient-derived preclinical models of liver cancer.

Novel patient-derived preclinical models of liver cancer.

Abstract Preclinical models of cancer based on the use of human cancer...

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Organoid of ovarian cancer: genomic analysis and...

Organoid of ovarian cancer: genomic analysis and drug screening.

Abstract Ovarian cancer is the most common malignant tumors of the female...

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Applications of patient-derived tumor xenograft models and...

Applications of patient-derived tumor xenograft models and tumor organoids.

Abstract Patient-derived tumor xenografts (PDXs), in which tumor fragments surgically dissected from...

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Could 3D models of cancer enhance drug...

Could 3D models of cancer enhance drug screening?

Abstract Cancer is a multifaceted pathology, where cellular and acellular players interact...

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Patient-Derived Colorectal Cancer Organoids Upregulate Revival Stem...

Patient-Derived Colorectal Cancer Organoids Upregulate Revival Stem Cell Marker Genes following Chemotherapeutic Treatment.

Abstract Colorectal cancer stem cells have been proposed to drive disease progression,...

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PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal...

PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo.

Abstract In most cancers, cellular origin and the contribution of intrinsic and...

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The promises and challenges of patient-derived tumor...

The promises and challenges of patient-derived tumor organoids in drug development and precision oncology.

Abstract In the era of precision medicine, cancer researchers and oncologists are...

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Wnt Signaling in 3D: Recent Advances in...

Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids.

Abstract Intestinal organoids grown from adult stem cells have emerged as prototype...

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