Organoid Research Group Publications

Developing models of cholangiocarcinoma to close the...

Developing models of cholangiocarcinoma to close the translational gap in cancer research

Abstract Cholangiocarcinoma (CCA) is an aggressive primary liver malignancy with abysmal prognosis...

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Ex vivo culture of intact human patient...

Ex vivo culture of intact human patient derived pancreatic tumour tissue

Abstract The poor prognosis of pancreatic ductal adenocarcinoma (PDAC) is attributed to...

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Future perspectives from lung cancer pre-clinical models:...

Future perspectives from lung cancer pre-clinical models: new treatments are coming?

Abstract Lung cancer currently stands out as both the most common and...

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Historical evolution of spheroids and organoids, and...

Historical evolution of spheroids and organoids, and possibilities of use in life sciences and medicine

Abstract Background: An impressive percentage of biomedical advances were achieved through animal...

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Organoid technology for personalized pancreatic cancer therapy

Organoid technology for personalized pancreatic cancer therapy

Abstract Background: Pancreatic ductal adenocarcinoma has the lowest survival rate among all...

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Semiconducting polymer nanoparticles for photothermal ablation of...

Semiconducting polymer nanoparticles for photothermal ablation of colorectal cancer organoids

Abstract Colorectal cancer (CRC) treatment is currently hindered by micrometastatic relapse that...

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A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid...

A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation

Abstract Mutations in ARID1A rank amongst the most common molecular aberrations in...

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Ethanol exposure drives colon location specific cell...

Ethanol exposure drives colon location specific cell composition changes in a normal colon crypt 3D organoid model

Abstract Alcohol is a consistently identified risk factor for colon cancer. However,...

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A 3D View of Colorectal Cancer Models...

A 3D View of Colorectal Cancer Models in Predicting Therapeutic Responses and Resistance

Abstract Although there have been many advances in recent years for the...

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