Patient-derived ovarian cancer organoids capture the genomic...

Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing

Abstract The use of primary patient-derived organoids for drug sensitivity and resistance...

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Current concepts in tumour-derived organoids

Current concepts in tumour-derived organoids

Abstract Cancer comprises a collection of highly proliferative and heterogeneous cells growing...

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Development of a miniaturized 3D organoid culture...

Development of a miniaturized 3D organoid culture platform for ultra-high throughput screening

Abstract The recent advent of robust methods to grow human tissues as...

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Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in...

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

Abstract Despite the development of second-generation antiandrogens, acquired resistance to hormone therapy...

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Patient-derived Organoid Pharmacotyping is a Clinically Tractable...

Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer

Abstract Objective: PDAC patients who undergo surgical resection and receive effective chemotherapy...

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Organoid Models of Tumor Immunology

Organoid Models of Tumor Immunology

Abstract Cellular interactions in the tumor microenvironment (TME) significantly govern cancer progression...

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A tissue-engineered 3D microvessel model reveals the...

A tissue-engineered 3D microvessel model reveals the dynamics of mosaic vessel formation in breast cancer

Abstract In solid tumors, vascular structure and function varies from the core...

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Intestinal organoids as tools for enriching and...

Intestinal organoids as tools for enriching and studying specific and rare cell types: advances and future directions

Abstract Adult tissue-derived organoids allow for the expansion and maintenance of primary...

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Patient-Derived In Vitro Models for Drug Discovery...

Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma

Abstract Lack of relevant preclinical models that reliably recapitulate the complexity and...

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