Organoid Research Group Publications

Allometric Scaling of physiologically-relevant organoids.

Allometric Scaling of physiologically-relevant organoids.

Abstract The functional and structural resemblance of organoids to mammalian organs suggests...

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Adult and iPS-derived non-parenchymal cells regulate liver...

Adult and iPS-derived non-parenchymal cells regulate liver organoid development through differential modulation of Wnt and TGF-β.

Abstract BACKGROUND: Liver organoid technology holds great promises to be used in...

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miR-221 targets QKI to enhance the tumorigenic...

miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells.

Abstract MicroRNAs (miRNAs) are key players in the integrated regulation of cellular...

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Molecular characterization of colorectal adenomas reveals POFUT1...

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

Abstract Removal of colorectal adenomas is an effective strategy to reduce colorectal...

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Biological Significance of Tumor Heterogeneity in Esophageal...

Biological Significance of Tumor Heterogeneity in Esophageal Squamous Cell Carcinoma.

Abstract Esophageal squamous cell carcinoma (ESCC) is a common and aggressive malignancy,...

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Mechanically and chemically defined hydrogel matrices for...

Mechanically and chemically defined hydrogel matrices for patient-derived colorectal tumor organoid culture.

Abstract Patient-derived tumor organoids offer potentially useful models of cancer tissue physiology....

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Disease modelling in human organoids.

Disease modelling in human organoids.

Abstract The past decade has seen an explosion in the field of...

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Senescence-associated tissue microenvironment promotes colon cancer formation...

Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15.

Abstract The risk of colorectal cancer (CRC) varies between people, and the...

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Patient-derived organoids from endometrial disease capture clinical...

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.

Abstract Endometrial disorders represent a major gynaecological burden. Current research models fail...

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