Senescence-associated tissue microenvironment promotes colon cancer formation...

Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15.

Abstract The risk of colorectal cancer (CRC) varies between people, and the...

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Patient-derived organoids from endometrial disease capture clinical...

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.

Abstract Endometrial disorders represent a major gynaecological burden. Current research models fail...

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HBV-related hepatocarcinogenesis: the role of signalling pathways...

HBV-related hepatocarcinogenesis: the role of signalling pathways and innovative ex vivo research models.

BACKGROUND: Hepatitis B virus (HBV) is the leading cause of liver cancer,...

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Organoid culture containing cancer cells and stromal...

Organoid culture containing cancer cells and stromal cells reveals that podoplanin-positive cancer-associated fibroblasts enhance proliferation of lung cancer cells.

OBJECTIVE: Podoplanin-positive cancer-associated fibroblasts (CAFs) play an important role in tumor progression....

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Generation of Tumor Organoids from Genetically Engineered...

Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer

Critical steps within the protocol for prostate tumor dissection and organoid generationRemoval...

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Xenograft and organoid model systems in cancer research

Xenograft and organoid model systems in cancer research

Introduction Cancers consist of a continuously evolving heterogeneous cell mass (McGranahan &...

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Morphophenotypic classification of tumor organoids as an...

Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential

AbstractThe dynamics of tumor progression is driven by multiple factors, which can...

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Liver organoids: from basic research to therapeutic...

Liver organoids: from basic research to therapeutic applications

IntroductionWhat are organoids? How can organoids benefit research?The study of human organ...

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