Organoid Research Group Publications

Once upon a dish: engineering multicellular systems.

Once upon a dish: engineering multicellular systems.

Abstract In February 2020, the European Molecular Biology Laboratory (EMBL) and the...

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Cancer-associated fibroblasts provide a stromal niche for...

Cancer-associated fibroblasts provide a stromal niche for liver cancer organoids that confers trophic effects and therapy resistance

Abstract Background & aims: Cancer associated fibroblasts (CAFs) play a key role...

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Organotypic Culture of Acinar Cells for the...

Organotypic Culture of Acinar Cells for the Study of Pancreatic Cancer Initiation

Abstract The carcinogenesis of pancreatic ductal adenocarcinoma (PDA) progresses according to multi-step...

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Establishment and Culture of Human Intestinal Organoids...

Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells

Abstract Human intestinal organoids derived from adult stem cells are miniature ex...

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Patient-derived ovarian cancer organoids capture the genomic...

Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing

Abstract The use of primary patient-derived organoids for drug sensitivity and resistance...

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Current concepts in tumour-derived organoids

Current concepts in tumour-derived organoids

Abstract Cancer comprises a collection of highly proliferative and heterogeneous cells growing...

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Development of a miniaturized 3D organoid culture...

Development of a miniaturized 3D organoid culture platform for ultra-high throughput screening

Abstract The recent advent of robust methods to grow human tissues as...

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Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in...

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

Abstract Despite the development of second-generation antiandrogens, acquired resistance to hormone therapy...

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Patient-derived Organoid Pharmacotyping is a Clinically Tractable...

Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer

Abstract Objective: PDAC patients who undergo surgical resection and receive effective chemotherapy...

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