Organoid Research Group Publications

Organoid Models of Tumor Immunology

Organoid Models of Tumor Immunology

Abstract Cellular interactions in the tumor microenvironment (TME) significantly govern cancer progression...

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A tissue-engineered 3D microvessel model reveals the...

A tissue-engineered 3D microvessel model reveals the dynamics of mosaic vessel formation in breast cancer

Abstract In solid tumors, vascular structure and function varies from the core...

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Intestinal organoids as tools for enriching and...

Intestinal organoids as tools for enriching and studying specific and rare cell types: advances and future directions

Abstract Adult tissue-derived organoids allow for the expansion and maintenance of primary...

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Patient-Derived In Vitro Models for Drug Discovery...

Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma

Abstract Lack of relevant preclinical models that reliably recapitulate the complexity and...

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Recommended Guidelines for Developing, Qualifying, and Implementing...

Recommended Guidelines for Developing, Qualifying, and Implementing Complex In Vitro Models (CIVMs) for Drug Discovery

Abstract The pharmaceutical industry is continuing to face high research and development...

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Metabolic Profiling of Early and Late Recurrent...

Metabolic Profiling of Early and Late Recurrent Pancreatic Ductal Adenocarcinoma Using Patient-Derived Organoid Cultures

Abstract Pancreatic ductal adenocarcinoma (PDAC) is associated with high mortality and will...

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Assessing the Origin of High-Grade Serous Ovarian...

Assessing the Origin of High-Grade Serous Ovarian Cancer Using CRISPR-modification of Mouse Organoids

Abstract High-grade serous ovarian cancer (HG-SOC)-often referred to as a "silent killer"-is...

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Identifying Predictors of HPV-related Head and Neck...

Identifying Predictors of HPV-related Head and Neck Squamous Cell Carcinoma Progression and Survival Through Patient-Derived Models

Abstract Therapeutic innovation for human papilloma virus-related (HPV+) head and neck squamous...

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“Tissues in a Dish”: A Review of...

“Tissues in a Dish”: A Review of Organoids in Plastic Surgery

Abstract Organoids are in vitro miniaturized organ models-or, colloquially, "organs in a...

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