Spheroids, Organoids Replacing Standard Cultures for Cell-Based Assays

Three-dimensional (3D) cell culture overcomes many shortcomings of two-dimensional (2D) culture, mainly through the introduction of biological relevance. Cells in three dimensions “see” and “feel” neighboring cells, interact with them through chemical messaging, and reprise physiologic events much more faithfully than cells restricted by the physical and mechanical constraints […]

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