Identifying Predictors of HPV-related Head and Neck Squamous Cell Carcinoma Progression and Survival Through Patient-Derived Models

Abstract Therapeutic innovation for human papilloma virus-related (HPV+) head and neck squamous cell carcinomas (HNSCCs) is impaired by inadequate preclinical models and absence of accurate biomarkers. This study establishes the first well-characterized panel of patient-derived xenografts (PDXs) and organoids from HPV+ HNSCCs while determining fidelity of the models to […]

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