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Prioritizing Gene Cascading Paths to Model Colorectal Cancer Through Engineered Organoids.

March 4, 2020

Abstract Engineered organoids by sequential introduction of key mutations could help modeling the dynamic cancer progression. However, it remains difficult to determine gene paths which were sufficient to capture cancer behaviors and to broadly explain cancer mechanisms. Here, as a case study of colorectal cancer (CRC), functional and dynamic […]

View Original Source at Prioritizing Gene Cascading Paths to Model Colorectal Cancer Through Engineered Organoids.

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