The kinase activity of ERBB3 contributes to intestinal organoids growth and intestinal tumorigenesis.

Abstract ERBB3, a member of the epidermal growth factor receptor (EGFR) family, plays an essential role in development and disease independent of inherently inactive kinase domain. Recently, ERBB3 has been found to bind to adenosine triphosphate (ATP) and has a catalytic activity in vitro. However, the biological function of […]

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